abstract：:Aboriginals experience high rates of end-stage renal disease (ESRD) and are less likely to receive a kidney transplant from a living donor. We hypothesized that higher rates of hypertension and diabetes in Aboriginal communities would result in fewer potential living donors coming forward and more exclusions for medic...

journal_title：Clinical transplantation

authors： Dunsmore S,Karpinski M,Young A,Storsley L

更新日期：2011-11-01 00:00:00

abstract：:Functioning nephron mass is a determinant of the graft function of kidney transplant recipients. The graft kidney volume and its weight have been reported to be surrogates of the nephron mass. To investigate the impact of the ratios of the surrogates to recipient body surface area (BSA) and body weight on the graft fu...

journal_title：Clinical transplantation

authors： Lee JH,Won JH,Oh CK

更新日期：2011-11-01 00:00:00

abstract：INTRODUCTION:In 2006, model for end-stage liver disease (MELD)-based allocation was implemented in the Eurotransplant (ET) region. Sick patients, who in general require more resources, are prioritized. In this analysis, the effect of MELD on costs for liver transplantation (LTx) was assessed. METHODS:Total costs for L...

journal_title：Clinical transplantation

authors： Bruns H,Hillebrand N,Schneider T,Hinz U,Fischer L,Schmidt J,Goldschmidt AJ,Schemmer P

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Progressive familial intrahepatic cholestasis (PFIC) results in liver cirrhosis. Therefore, some PFIC patients require liver transplantation (LT). Although three types of PFIC have been identified, their etiologies include unknown mechanisms. PATIENTS:A total of 717 recipients who underwent living-donor LT ...

journal_title：Clinical transplantation

authors： Hori T,Egawa H,Takada Y,Ueda M,Oike F,Ogura Y,Sakamoto S,Kasahara M,Ogawa K,Miyagawa-Hayashino A,Yonekawa Y,Yorifuji T,Watanabe K,Doi H,Nguyen JH,Chen F,Baine AM,Gardner LB,Uemoto S

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The proportion of prospective living donors disqualified for medical reasons is unknown. The objective of this study is to delineate and quantify specific reasons for exclusion of prospective living donors from kidney donation. METHODS:All adult prospective kidney donors who contacted our transplant program...

journal_title：Clinical transplantation

authors： Lapasia JB,Kong SY,Busque S,Scandling JD,Chertow GM,Tan JC

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To clarify the predictive impact of expanded criteria for liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) in 54 patients with HCC beyond the Milan criteria (MC) from a series of 109 consecutive living-related donor liver transplantation (LDLT) recipients with HCC. METHODS:Among 54...

journal_title：Clinical transplantation

authors： Shirabe K,Taketomi A,Morita K,Soejima Y,Uchiyama H,Kayashima H,Ninomiya M,Toshima T,Maehara Y

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Everolimus (EVL) and sirolimus (SRL) were introduced into immunosuppressive regimens, in an attempt to replace or reduce the dose of the nephrotoxic calcineurin inhibitors (CNI). In our institution, due to an administrative decision, conversion from SRL to EVL, was carried out, providing us the opportunity t...

journal_title：Clinical transplantation

authors： Carvalho C,Coentrão L,Bustorff M,Patrício E,Sampaio S,Santos J,Oliveira G,Pestana M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Cyclosporine (CsA) and tacrolimus (Tac) in heart transplantation (HTx) have been compared but with certain drawbacks. We compared both drugs in a prospective analysis with medium-term follow-up. METHODS:Hundred and six patients were randomized to receive CsA or Tac (53 per group). Target levels of CsA were ...

journal_title：Clinical transplantation

authors： Sánchez-Lázaro IJ,Almenar L,Martínez-Dolz L,Buendía-Fuentes F,Agüero J,Navarro-Manchón J,Vicente JL,Salvador A

更新日期：2011-07-01 00:00:00

abstract：:There is paucity in the data examining the differences in mycophenolate mofetil (MMF) dosing and outcomes among pediatric kidney transplant recipients (PKTX) between races. The aims of this study were as follows (i) to assess whether higher doses of MMF are being utilized in African American (AA) PKTX (ii) to determin...

journal_title：Clinical transplantation

authors： Jensen CJ,Shrivastava S,Taber DJ,Weimert NA,Shatat IF,Orak J,Chavin KD,Baliga PK

更新日期：2011-07-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) have been commonly used as pivotal immunosuppressive agents to renal transplant recipients and have contributed significantly to improving short-term allograft survival. However, long-term administration of CNI may cause an adverse effect on kidney function, known as chronic nephrotoxicity...

journal_title：Clinical transplantation

authors： Horike K,Takeda A,Yamaguchi Y,Ogiyama Y,Yamauchi Y,Murata M,Kawaguchi T,Suzuki T,Otsuka Y,Inaguma D,Goto N,Watarai Y,Uchida K,Morozumi K

更新日期：2011-07-01 00:00:00

abstract：:Post-transplant outcome of kidney allografts depends on various factors, one of which may be the compatibility in volume between graft and recipient. However, previous studies adjusted the graft volume only for recipient's size. As the adjusted graft volume for donor's size would be substituted of nephron number more ...

journal_title：Clinical transplantation

authors： Han SS,Yang SH,Oh YJ,Cho JY,Moon KC,Ha J,Kim YS

更新日期：2011-05-01 00:00:00

abstract：:Xenotransplantation is a potential strategy to overcome the shortage of human donor organs. As this technique has a major medical and psychological impact on patients and their family and friends, the attitude of patients currently waiting for organ transplantation is important. Therefore, we conducted a survey on the...

journal_title：Clinical transplantation

authors： Stadlbauer V,Stiegler P,Müller S,Schweiger M,Sereingg M,Tscheliessnigg KH,Freidl W

更新日期：2011-05-01 00:00:00

abstract：:Obesity has reached epidemic proportions in the USA. Consequently, there are an increasing number of potential organ donors that are obese, but would otherwise be appropriate donors for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University between 2003 and 2009 (n = 3...

journal_title：Clinical transplantation

authors： Fridell JA,Mangus RS,Taber TE,Goble ML,Milgrom ML,Good J,Vetor R,Powelson JA

更新日期：2011-05-01 00:00:00

abstract：:Liver transplant (LT) outcomes are reported to be improving in non-HCV recipients but not for those infected with HCV. Our aim was to evaluate graft survival and predictors of outcome in HCV and non-HCV patients before and after 2003. Patients with primary LT between February 1, 1998, and December 31, 2005, were inclu...

journal_title：Clinical transplantation

authors： Dickson RC,Pungpapong S,Keaveny AP,Taner CB,Ghabril M,Aranda-Michel J,Satyanarayana R,Bonatti H,Kramer DJ,Nguyen JH

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is an indication for orthotopic liver transplantation (OLT) in patients with tumor stage within the United Network for Organ Sharing criteria. The number of patients listed for HBV-related HCC is increasing, while the number of patients listed fo...

journal_title：Clinical transplantation

authors： Han SH,Reddy KR,Keeffe EB,Soldevila-Pico C,Gish R,Chung RT,Degertekin B,Lok A,NIH HBV OLT Study Group.

更新日期：2011-03-01 00:00:00

abstract：:Acute renal failure is a significant risk factor for death in patients with liver failure. The goal of this study was to analyze the impact of peri-transplant dialysis on the long-term mortality of liver transplant recipients. We performed a single-center, retrospective cohort study of 743 adult liver transplants; pat...

journal_title：Clinical transplantation

authors： Zand MS,Orloff MS,Abt P,Patel S,Tsoulfas G,Kashyap R,Jain A,Safadjou S,Bozorgzadeh A

更新日期：2011-03-01 00:00:00

abstract：:We examined the UNOS database from 7/15/00-7/17/05 for Regional deceased donor liver utilization. For each region, we performed logistic regression and derived odds ratios (OR) for donor characteristics associated with livers being transplanted outside of the region or not transplanted at all. Regions with smallest an...

journal_title：Clinical transplantation

authors： Hayashi PH,Axelrod DA,Galanko J,Salvalaggio PR,Schnitzler M

更新日期：2011-01-01 00:00:00

abstract：:In recent years, several researchers have unraveled the previously unrecognized effects of granulocyte colony-stimulating factor (G-CSF) on hematopoiesis and the immune cell functions of bone marrow in healthy donors. In human leukocyte antigen-matched or haploidentical transplant settings, available data have establi...

journal_title：Clinical transplantation

authors： Chang YJ,Huang XJ

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to improve outcomes in living donor liver transplantation (LDLT) patients with portal vein thrombosis (PVT). Of 246 adult patients who underwent LDLT with a right lobe graft between January 2000 and May 2007, PVT was diagnosed in 50 patients (20.3%), who were further subdivided into partial (...

journal_title：Clinical transplantation

authors： Kim SJ,Kim DG,Park JH,Moon IS,Lee MD,Kim JI,Yoon YC,Yoo YK

更新日期：2011-01-01 00:00:00

abstract：:Multidetector computed tomography (MDCT) angiography is a reliable technique for assessing pre-operative renal anatomy in living kidney donors. The method has largely evolved into protocols that eliminate dedicated venous phase and instead utilize a combined arterial/venous phase to delineate arterial and venous anato...

journal_title：Clinical transplantation

authors： Kulkarni S,Emre S,Arvelakis A,Asch W,Bia M,Formica R,Israel G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:One severe side effect of calcineurin inhibitors (CNIs: such as cyclosporine [CsA] and tacrolimus [FK506]) is neurotoxicity. CNIs are substrates for CYP3A5 and P-glycoprotein (P-gp), encoded by ABCB1 gene. In the present study, we hypothesized that genetic variability in CYP3A5 and ABCB1 genes may be associa...

journal_title：Clinical transplantation

authors： Yanagimachi M,Naruto T,Tanoshima R,Kato H,Yokosuka T,Kajiwara R,Fujii H,Tanaka F,Goto H,Yagihashi T,Kosaki K,Yokota S

更新日期：2010-11-01 00:00:00

abstract：:This prospective study aimed at determining the ganciclovir exposure observed under a daily dosage of 450 mg valganciclovir routinely applied to kidney transplant recipients with a GFR above 25 mL/min at risk for cytomegalovirus (CMV) disease. Ganciclovir levels at trough (C(trough)) and at peak (C₃(h)) were measured ...

journal_title：Clinical transplantation

authors： Manuel O,Pascual M,Perrottet N,Lamoth F,Venetz JP,Decosterd LA,Buclin T,Meylan PR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Patients on organ transplant waiting lists continue to far exceed donor rates. We seek to understand the barriers preventing people in a Canadian city from donating organs for transplantation. METHODS:One thousand adults were surveyed assessing knowledge, personal involvement, and attitudes about organ dona...

journal_title：Clinical transplantation

authors： Lee E,Midodizi W,Gourishankar S

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To determine whether depressive symptoms predicted survival before and after lung transplantation. We hypothesized that depressive symptoms might predict survival of wait-listed patients, but would not predict survival post-transplant. METHODS:This was a prospective, longitudinal study. Participants complete...

journal_title：Clinical transplantation

authors： Evon DM,Burker EJ,Galanko JA,Dedert E,Egan TM

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:The average age of patients undergoing liver transplantation (LT) is consistently increasing. The aim of this case-control study is to evaluate survival and outcome of patients ≥65 yr compared to younger patients undergoing LT. MATERIALS AND METHODS:From 10/00 to 4/08 we performed 330 primary LT, 31 (9.4%...

journal_title：Clinical transplantation

authors： Montalti R,Rompianesi G,Di Benedetto F,Ballarin R,Gerring RC,Busani S,De Pietri L,De Ruvo N,Iemmolo RM,Guerrini GP,Smerieri N,Gerunda GE

更新日期：2010-09-01 00:00:00

abstract：:Post-transplant bone disease is common in solid organ recipients; however, there is limited information on their pre-transplant bone status. We aimed to compare bone mineral density (BMD) in different categories of patients with end-stage organ failure awaiting transplantation (Tx) in Norway. Overall 291 adult patient...

journal_title：Clinical transplantation

authors： Dolgos S,Hartmann A,Isaksen GA,Simonsen S,Bjørtuft Ø,Boberg KM,Bollerslev J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:To assess the diagnostic value of magnetic resonance cholangiography (MRC) when evaluating biliary complications in a large series of liver transplants. METHODS:One hundred and twenty-nine patients prospectively underwent magnetic resonance (MR) imaging and MR cholangiography at 1.5-T device after orthotopi...

journal_title：Clinical transplantation

authors： Boraschi P,Donati F,Gigoni R,Volpi A,Salemi S,Filipponi F,Falaschi F

更新日期：2010-07-01 00:00:00

abstract：:Because the safety of living organ donors is essential, we have been performing donor kidney biopsy before donation in cases where decision-making regarding suitability is marginal. To clarify the degree to which pathological change in the kidney can be predicted on the basis of clinical data obtained non-invasively, ...

journal_title：Clinical transplantation

authors： Okamoto M,Koshino K,Nobori S,Ushigome H,Okajima H,Urasaki K,Yoshimura N

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The survival of patients returning to hemodialysis (HD) following kidney transplant failure is unfavorable. However, the factors responsible for this poor outcome are largely unknown; chronic inflammation due to failed allograft and malnutrition may contribute to morbidity and mortality. We aimed to compare ...

journal_title：Clinical transplantation

authors： Yelken BM,Gorgulu N,Caliskan Y,Yazici H,Turkmen A,Yildiz A,Sever MS

更新日期：2010-07-01 00:00:00

abstract：:This multicenter, randomized trial aimed to compare the safety and efficacy of an early reduction in corticosteroid dose vs. long-term maintenance in Brazilian patients on an immunosuppressive regimen based on tacrolimus and mycophenolate mofetil (MMF). In the control arm, prednisone was progressively reduced from day...

journal_title：Clinical transplantation

authors： Garcia VD,Carvalho DB,Gonçalves RT,Cavalcanti RL,Campos HH,Abbud-Filho M,Lobao-Neto AA

更新日期：2010-07-01 00:00:00

abstract：:In a cohort of 32 renal transplant patients who are potentially at risk for adverse events, we compared tacrolimus (TAC) abbreviated AUC values calculated by a method developed in Asians (AUCw) with those derived for Caucasians (AUCa). The relationships between TAC trough (C0), abbreviated AUC, and biopsy results were...

journal_title：Clinical transplantation

authors： Hon YY,Chamberlain CE,Kleiner DE,Ring MS,Hale DA,Kirk AD,Mannon RB

更新日期：2010-07-01 00:00:00

abstract：:Kidney transplantation offers longer survival, less morbidity and lower costs than dialysis. It is also believed to improve quality of life. The aim of this study was to compare prospectively the perceived health status (PHS) of dialyzed patients on a waiting list with kidney transplant recipients after transplantatio...

journal_title：Clinical transplantation

authors： Rosenberger J,van Dijk JP,Prihodova L,Majernikova M,Nagyova I,Geckova AM,Roland R,van den Heuvel WJ,Groothoff JW

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. METHODS:A cross-sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosu...

journal_title：Clinical transplantation

authors： Chisholm-Burns MA,Spivey CA,Wilks SE

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:Laparoscopy is a standard surgical option for live donor nephrectomy (LDN) at the majority of transplant centers. Equivalent graft survival with shorter convalescence has been reported by several large volume centers. With the arrival of an experienced laparoscopic surgeon in 2002, we began to offer laparo...

journal_title：Clinical transplantation

authors： Riley J,Troxel S,Wakefield M,Ross G,Weinstein S

更新日期：2010-05-01 00:00:00

abstract：:Pancreas retransplantation has become more frequent and represents a technical challenge for surgeons. Knowledge of alternative surgical options could be useful in difficult cases. We present a case of brutal diabetes mellitus in a patient with severe vascular disease that underwent a third pancreas transplant. Diffic...

journal_title：Clinical transplantation

authors： Garcia-Roca R,Humar A,Sturdevant M,Kobayashi T,Dunn T,Kandaswamy R,Sutherland D

更新日期：2010-05-01 00:00:00

abstract：:According to the EU Directive 2006/17/EC, European tissue banks are required to perform a physical examination on every potential tissue donor. The directive itself, however, does not specify the content of this examination. The aim of this study was to investigate the current practice of physical examination in Europ...

journal_title：Clinical transplantation

authors： Van Geyt C,Van Wijk M,Bokhorst A,Beele H

更新日期：2010-03-01 00:00:00

abstract：:Temporary portocaval shunt and total hepatectomy is a technique used in the presence of toxic liver syndrome because of fulminant hepatic failure, hepatic trauma, primary non-function (PNF), and eclampsia. We performed this technique on four patients. An indication for anhepatic state was severe hemodynamic instabilit...

journal_title：Clinical transplantation

authors： Montalti R,Busani S,Masetti M,Girardis M,Di Benedetto F,Begliomini B,Rompianesi G,Rinaldi L,Ballarin R,Pasetto A,Gerunda GE

更新日期：2010-01-01 00:00:00

abstract：:Whole pancreas and islet cell transplantation are both reliant upon the procurement and preservation of a high quality donor pancreas for a successful outcome. In the climate of a reducing donor pool it is imperative that donor optimization, meticulous surgical retrieval and evidence based methods of preservation are ...

journal_title：Clinical transplantation

authors： Ridgway D,Manas D,Shaw J,White S

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Recurrence of hepatitis C virus (HCV) in hepatic allograft is a major concern after successful liver transplant (LTx). AIM:To examine the response rate to pegylated interferon (PEG-IFN) and ribavirin in post-LTx patients with HCV recurrence. PATIENTS AND METHODS:Between January 2003 and September 2006, 6...

journal_title：Clinical transplantation

authors： Jain A,Sharma R,Ryan C,Safadjou S,Kashyap R,Mantry P,Maliakkal B,Orloff M

更新日期：2010-01-01 00:00:00

abstract：:Transplantation tolerance is the ultimate goal of organ transplantation. Natural regulatory T cells (Treg) have been expected to reach clinical applications for tolerance induction because their initial description. More than ten yr later, Treg have started moving from experimental animal models into clinical applicat...

journal_title：Clinical transplantation

authors： Fritzsching E,Kunz P,Maurer B,Pöschl J,Fritzsching B

更新日期：2009-12-01 00:00:00